Rook's Textbook of Dermatology, 4 Volume Set, 9th Edition by Christopher Griffiths (Editor), Jonathan Barker (Editor), Tanya Bleiker (Editor), Robert Chalmers (Editor), Daniel Creamer (Editor)

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2017 PROSE Award Winner - Multivolume Reference/Science 

The world's number 1 dermatology information resource

Universally respected, Rook's Textbook of Dermatology is the most comprehensive, definitive and best-illustrated reference work for dermatologists of all levels worldwide and has been at the forefront of international dermatology publishing since first appearing in 1968.

The Ninth Edition has been radically re-engineered to match the modern day challenges faced by dermatologists. Once again it has been published as a combined digital and print resource, but with a new online platform enabling easier and faster navigation.

A common structure to describe and discuss each disorder has been adopted throughout, whilst maintaining the depth of information for which Rook is renowned. A high priority has been placed on the ease of extracting key information quickly: diagnostic algorithms and management ladders help the reader choose appropriate treatment strategies. More images than ever – over 5000 in total – aid diagnosis by displaying variations in disease manifestations according to body location, skin type and severity. The section on aesthetic dermatology has been greatly expanded with more coverage of procedures in this rapidly developing field.

Rook's Textbook of Dermatology, Ninth Edition provides you with:

  • The very best content from the number one brand in dermatology – an essential consultation tool for all dermatologists
  • An outstanding combined digital/print resource, exhaustively covering every dermatological disorder
  • A complete overhaul of its content – each disorder now follows a consistent templated approach
  • A fresh approach to the classification of disorders and organization of chapters, of which there are now 160 instead of 80, all organised into 14 logical sections
  • A newly designed sophisticated online platform with a fast and powerful digital search functionality – search by keyword, disorder or chapter or consult the online image database and get expert clinical advice more quickly than ever
  • Lavishly illustrated chapters with over 5000 colour images showing variation in disease patterns by body location, skin type and severity
  • Comprehensive coverage of medical, surgical and aesthetic dermatology, as well as the basic science underpinning the field
  • An experienced British editorial team working with distinguished international authors and associate editor
  • Greater emphasis than before on clinical studies/trials, society guidelines and the latest ICD codes
  • While key references remain in the printed version, thousands more are cited in the book and can be accessed online, where each is hyperlinked to the relevant text

Rook’s Textbook of Dermatology, Ninth Edition is the complete dermatology reference work. More comprehensive than ever, with more images, more disorders covered and faster, more dynamic and wider digital search functionality. It is an essential resource for the modern day dermatologist, whether experienced or at the beginning of a career in dermatology.


Table of Contents

List of Associate Editors

List of Contributors

Preface to the Ninth Edition

Preface to the First Edition


Part 1 Foundations of Dermatology

1 History of Dermatology
Nick J. Levell

2 Structure and Function of the Skin
John A. McGrath and Jouni Uitto

3 Histopathology of the Skin: General Principles
Eduardo Calonje with a contribution from Balbir S. Bhogal (Immunofluorescence techniques)

4 Diagnosis of Skin Disease
Ian H. Coulson, Emma C. Benton and Stephanie Ogden

5 Epidemiology of Skin Disease
Hywel C. Williams

6 Health Economics and Skin Disease
Matthias Augustin and Magdalene Krensel

7 Genetics and the Skin
John A. McGrath

8 Inflammation, Immunology and Allergy
Martin Steinhoff

9 Photobiology
Antony R. Young

10 Cutaneous Response to Injury and Wound Healing
Edel A. O’Toole

11 Psychological and Social Impact of Long-term Dermatological Conditions
Christine Bundy and Lis Cordingley

12 Adverse Immunological Reactions to Drugs
Michael R. Ardern‐Jones

13 Topical Drug Delivery
Richard H. Guy

14 Clinical Pharmacology
Catherine H. Smith

Part 2 Management

15 Principles of Holistic Management of Skin Disease
Sam Gibbs

16 Principles of Measurement and Assessment in Dermatology
Andrew Y. Finlay

17 Principles of Evidence‐based Dermatology
Michael Bigby and Hywel C. Williams

18 Principles of Topical Therapy
John Berth‐Jones

19 Principles of Systemic Therapy
Michael J. Tidman and Catherine H. Smith

20 Principles of Skin Surgery
S. Walayat Hussain, Richard J. Motley and Timothy S. Wang

21 Principles of Phototherapy
Kevin McKenna and Sally Ibbotson

22 Principles of Photodynamic Therapy
Sally Ibbotson and Kevin McKenna

23 Principles of Cutaneous Laser Therapy
Vishal Madan and Richard J. Barlow

24 Principles of Radiotherapy
Charles G. Kelly and John Frew

Part 3 Infections and Infestations

25 Viral Infections
Jane C. Sterling

26 Bacterial Infections
Roderick J. Hay and Rachael Morris‐Jones

27 Mycobacterial Infections
Victoria M. Yates and Stephen L. Walker

28 Leprosy
Diana N. J. Lockwood

Introduction to Chapters 29 and 30: Global Overview of Sexually Transmitted Infections
George R. Kinghorn and Rasha Omer

29 Syphilis and Congenital Syphilis
George R. Kinghorn and Rasha Omer

30 Other Sexually Transmitted Bacterial Diseases
George R. Kinghorn, Aparna Briggs and Nadi K. Gupta

31 HIV and the Skin
Christopher B. Bunker and Vincent Piguet

32 Fungal Infections
Roderick J. Hay and H. Ruth Ashbee

33 Parasitic Diseases
Christopher Downing and Stephen Tyring

34 Arthropods
Gentiane Monsel, Pascal Delaunay and Olivier Chosidow



Part 4 Inflammatory Dermatoses

35 Psoriasis and Related Disorders
A. David Burden and Brian Kirby

36 Pityriasis Rubra Pilaris
Anthony C. Chu

37 Lichen Planus and Lichenoid Disorders
Vincent Piguet, Stephen M. Breathnach and Laurence Le Cleach

38 Graft‐versus‐host Disease
Tanya N. Basu

39 Eczematous Disorders
John R. Ingram

40 Seborrhoeic Dermatitis
Sarah Wakelin

41 Atopic Eczema
Michael R. Ardern‐Jones, Carsten Flohr, Nick J. Reynolds and Colin A. Holden

42 Urticaria
Clive E. H. Grattan and Alexander M. Marsland

43 Recurrent Angio‐oedema without Weals
Clive E. H. Grattan and Marcus Maurer

44 Urticarial Vasculitis
Elena Borzova and Clive E. H. Grattan

45 Autoinflammatory Diseases Presenting in the Skin
Dan Lipsker, Clive E. H. Grattan and Christopher R. Lovell

46 Mastocytosis
Clive E. H. Grattan and Deepti H. Radia

47 Reactive Inflammatory Erythemas
Malcolm Rustin and Rino Cerio

48 Adamantiades–Behçet Disease
Christos C. Zouboulis

49 Neutrophilic Dermatoses
Anthony D. Ormerod and Philip J. Hampton

50 Immunobullous Diseases
Enno Schmidt and Richard Groves

51 Lupus Erythematosus
Mark Goodfield, Jan Dutz and Collette McCourt

52 Antiphospholipid Syndrome
Mark Goodfield and Shyamal Wahie

53 Dermatomyositis
Patrick Gordon and Daniel Creamer

54 Mixed Connective Tissue Disease
Mark Goodfield

55 Dermatological Manifestations of Rheumatoid Disease
Mark Goodfield

56 Systemic Sclerosis
Catherine H. Orteu and Christopher P. Denton

57 Morphoea and Allied Scarring and Sclerosing Inflammatory Dermatoses
Catherine H. Orteu

Part 5 Metabolic and Nutritional Disorders Affecting the Skin

58 Cutaneous Amyloidoses
Stephan Schreml

59 Cutaneous Mucinoses
Franco Rongioletti

60 Cutaneous Porphyrias
Robert P. E. Sarkany

61 Calcification of the Skin and Subcutaneous Tissue
Johnny Bourke

62 Xanthomas and Abnormalities of Lipid Metabolism and Storage
Paul D. Flynn

63 Nutritional Disorders Affecting the Skin
Derek H. Chu, Melinda V. Jen and Albert C. Yan

64 Skin Disorders in Diabetes Mellitus
Johnny Bourke

Part 6 Genetic Disorders Involving the Skin

65 Inherited Disorders of Cornification
Vinzenz Oji, Dieter Metze and Heiko Traupe

66 Inherited Acantholytic Disorders
Mozheh Zamiri and Colin S. Munro

67 Ectodermal Dysplasias
Peter Itin

68 Inherited Hair Disorders
Eli Sprecher

69 Genetic Defects of Nails and Nail Growth
Adam Rubin and Amy S. Paller

70 Genetic Disorders of Pigmentation
Alain Taieb, Fanny Morice‐Picard and Khaled Ezzedine

71 Genetic Blistering Diseases
John A. McGrath

72 Genetic Disorders of Collagen, Elastin and Dermal Matrix
Nigel Burrows

73 Disorders Affecting Cutaneous Vasculature
Anne Dompmartin, Nicole Revencu, Laurence M. Boon and Miikka Vikkula

74 Genetic Disorders of Adipose Tissue
George W. M. Millington

75 Congenital Naevi and Other Developmental Abnormalities Affecting the Skin
Veronica A. Kinsler and Neil J. Sebire

76 Chromosomal Disorders
Alan D. Irvine and Jemima E. Mellerio

77 Poikiloderma Syndromes
Alan D. Irvine and Jemima E. Mellerio

78 DNA Repair Disorders with Cutaneous Features
Hiva Fassihi

79 Syndromes with Premature Ageing
Alan D. Irvine and Jemima E. Mellerio

80 Hamartoneoplastic Syndromes
Alan D. Irvine and Jemima E. Mellerio

81 Inherited Metabolic Diseases
Andrew Morris

82 Inherited Immunodeficiency
Tim Niehues and Andrew R. Gennery

Part 7 Psychological, Sensory and Neurological Disorders and the Skin

83 Pruritus, Prurigo and Lichen Simplex
Sonja Stander and Malcolm Greaves

84 Mucocutaneous Pain Syndromes
Joanna M. Zakrzewska and Anthony Bewley

85 Neurological Conditions Affecting the Skin
David J. Eedy

86 Psychodermatology and Psychocutaneous Disease
Anthony Bewley and Ruth E. Taylor



Part 8 Skin Disorders Associated with Specific Cutaneous Structure

87 Acquired Disorders of Epidermal Keratinization
Anthony C. Chu and Fernanda Teixeira

88 Acquired Pigmentary Disorders
Nanja van Geel and Reinhart Speeckaert

89 Acquired Disorders of Hair
Andrew G. Messenger, Rodney D. Sinclair, Paul Farrant and David A. R. de Berker

90 Acne
Alison M. Layton, E. Anne Eady and Christos C. Zouboulis

91 Rosacea
Frank C. Powell

92 Hidradenitis Suppurativa
Nemesha Desai, Hessel H. van der Zee and Gregor B. E. Jemec

93 Other Acquired Disorders of the Pilosebaceous Unit
Roderick J. Hay, Rachael Morris‐Jones and Gregor B. E. Jemec

94 Disorders of the Sweat Glands
Ian H. Coulson and Niall J. E. Wilson

95 Acquired Disorders of the Nails and Nail Unit
David A. R. de Berker, Bertrand Richert and Robert Baran

96 Acquired Disorders of Dermal Connective Tissue
Christopher R. Lovell

97 Granulomatous Disorders of the Skin
Johnny Bourke

98 Sarcoidosis
Joaquim Marcoval and Juan Mana

99 Panniculitis
Luis Requena

100 Other Acquired Disorders of Subcutaneous Fat
Amy Y.‐Y. Chen and Amit Garg

Part 9 Vascular Disorders Involving the Skin

101 Purpura
Tabi A. Leslie

102 Cutaneous Vasculitis
Nick J. Levell and Chetan Mukhtyar

103 Dermatoses Resulting from Disorders of the Veins and Arteries
Portia C. Goldsmith

104 Ulceration Resulting from Disorders of the Veins and Arteries
Jurg Hafner

105 Disorders of the Lymphatic Vessels
Peter S. Mortimer and Kristiana Gordon

106 Flushing and Blushing
Siona Ni Raghallaigh and Frank C. Powell

Part 10 Skin Disorders Associated with Specific Sites, Sex and Age

107 Dermatoses of the Scalp
Paul Farrant, Megan Mowbray and Rodney D. Sinclair

108 Dermatoses of the External Ear
Cameron Kennedy

109 Dermatoses of the Eye, Eyelids and Eyebrows
Valerie P. J. Saw and Jonathan N. Leonard

110 Dermatoses of the Oral Cavity and Lips
Crispian Scully

111 Dermatoses of the Male Genitalia
Christopher B. Bunker and William M. Porter

112 Dermatoses of the Female Genitalia
Fiona Lewis

113 Dermatoses of Perineal and Perianal Skin
Eleanor Mallon

114 Cutaneous Complications of Stomas and Fistulae
Calum Lyon

115 Dermatoses of Pregnancy
Samantha Vaughan Jones

116 Dermatoses of the Neonate
David G. Paige

117 Dermatoses and Haemangiomas of Infancy
Elisabeth M. Higgins and Mary T. Glover



Part 11 Skin Disorders Caused by External Agents

118 Benign Cutaneous Adverse Reactions to Drugs
Michael R. Ardern‐Jones and Haur Yueh Lee

119 Severe Cutaneous Adverse Reactions to Drugs
Sarah Walsh, Haur Yueh Lee and Daniel Creamer

120 Cutaneous Side Effects of Chemotherapy and Radiotherapy
Louise Fearfield and Janakan Natkunarajah

121 Dermatoses Induced by Illicit Drugs
Daniel Creamer and Michael Gossop

122 Dermatological Manifestations of Metal Poisoning
Rabindranath Nambi

123 Mechanical Injury to the Skin
Saqib J. Bashir and Ai‐Lean Chew

124 Pressure Injury and Pressure Ulcers
Robyn Evans, Carol Ott and Madhuri Reddy

125 Cutaneous Reactions to Cold and Heat
Saqib J. Bashir and Ai‐Lean Chew

126 Burns and Heat Injury
Marc G. Jeschke

127 Cutaneous Photosensitivity Diseases
Sally Ibbotson and Robert Dawe

128 Allergic Contact Dermatitis
Mark Wilkinson and David Orton

129 Irritant Contact Dermatitis
Jonathan M. L. White

130 Occupational Dermatology
Jonathan M. L. White

131 Stings and Bites
Stephen Tyring and Christopher Downing

Part 12 Neoplastic, Proliferative and Infiltrative Disorders Affecting the Skin

132 Benign Melanocytic Proliferations and Melanocytic Naevi
Irene Stefanaki, Christina Antoniou and Alexander Stratigos

133 Benign Keratinocytic Acanthomas and Proliferations
Vishal Madan and John T. Lear

134 Cutaneous Cysts
John T. Lear and Vishal Madan

135 Lymphocytic Infiltrates
Fiona Child and Sean J. Whittaker

136 Cutaneous Histiocytoses
Thai Hoa Tran, Elena Pope and Sheila Weitzman

137 Soft‐tissue Tumours and Tumour‐like Conditions
Eduardo Calonje

138 Tumours of Skin Appendages
Eduardo Calonje

139 Kaposi Sarcoma
Kenneth Y. Tsai

140 Cutaneous Lymphomas
Sean J. Whittaker and Fiona Child

141 Basal Cell Carcinoma
Vishal Madan and John T. Lear

142 Squamous Cell Carcinoma and its Precursors
Girish Gupta, Vishal Madan and John T. Lear

143 Melanoma
Melanoma Clinicopathology

Jean Jacques Grob and Caroline Gaudy‐Marqueste

Melanoma Surgery
Kelly B. Cha, Timothy M. Johnson and Alison B. Durham

Systemic Treatment of Melanoma
Reinhard Dummer and Simone M. Goldinger

144 Dermoscopy of Melanoma and Naevi
Natalia Jaimes and Ashfaq A. Marghoob

145 Merkel Cell Carcinoma
Jürgen C. Becker, David Schrama and Axel zur Hausen

146 Skin Cancer in the Immunocompromised Patient
Catherine A. Harwood, Jane M. McGregor and Charlotte M. Proby

Part 13 Systemic Disease and the Skin

147 Cutaneous Markers of Internal Malignancy
Lennart Emtestam and Karin Sartorius

148 The Skin and Disorders of the Haematopoietic and Immune Systems
Robert Gniadecki

149 The Skin and Endocrine Disorders
Ralf Paus

150 The Skin and Disorders of the Heart
Sonja Molin and Thomas Ruzicka

151 The Skin and Disorders of the Respiratory System
Sonja Molin and Thomas Ruzicka

152 The Skin and Disorders of the Digestive System
Sonja Molin and Thomas Ruzicka

153 The Skin and Disorders of the Kidney and Urinary Tract
Sonja Molin and Thomas Ruzicka

154 The Skin and Disorders of the Musculoskeletal System
Christopher R. Lovell

Part 14 Aesthetic Dermatology

155 Skin Ageing
Dana L. Sachs, Gary Fisher and John J. Voorhees

156 Cosmeceuticals
Eubee Koo, Alexandra B. Kimball and Molly Wanner

157 Soft Tissue Augmentation (Fillers)
Berthold Rzany

158 Aesthetic Uses of Botulinum Toxins
Nicholas J. Lowe

159 Chemical Peels
Chee‐Leok Goh and Joyce Teng Ee Lim

160 Lasers and Energy‐based Devices
Nazanin Saedi and Christopher B. Zachary

Author Information

Professor Chris Griffiths, BSc, MB BS, FRCP, FRCPath, University of Manchester, Manchester, UK

Professor Jonathan Barker, BSc MD, FRCP, FRCPath, St John’s Institute of Dermatology, London, UK

Dr Tanya O. Bleiker, MB BS, MRCP, Derby Royal Infirmary, Derby, UK

Dr Robert J. G. Chalmers, MB, FRCP, University of Manchester, Manchester, UK

Dr J. Daniel Creamer, BSc, MD, FRCP, King’s College Hospital, London, UK

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