Textbook of Clinical Trials Second edition

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Textbook of Clinical Trials
Second edition

edited by
David Machin

 


Now published in its Second Edition, the Textbook of Clinical Trials offers detailed coverage of trial methodology in diverse areas of medicine in a single comprehensive volume.

The book's main concept is to describe the impact of clinical trials on the practice of medicine. It separates the information by therapeutic area because the impact of clinical trials, the problems encountered, and the numbers of trials in existence vary tremendously from specialty to specialty.

The sections provide a background to the disease area and general clinical trial methodology before concentrating on particular problems experienced in that area. Specific examples are used throughout to address these issues.

Features:

Highlights the various ways clinical trials have influenced the practice of medicine in many therapeutic areas
Describes the challenges posed by those conducting clinical trials over a range of medical specialities and allied fields
Additional therapeutic areas are included in this Second Edition to fill gaps in the First Edition as the number and complexity of trials increases in this rapidly developing area
Newly covered or updated in the Second Edition: general surgery, plastic surgery, aesthetic surgery, palliative care, primary care, anaesthesia and pain, transfusion, wound healing, maternal and perinatal health, early termination, organ transplants, ophthalmology, epilepsy, infectious disease, neuro-oncology, adrenal, thyroid and urological cancers, as well as a chapter on the Cochrane network
Textbook of Clinical Trials, Second Edition is an invaluable resource for pharmaceutical companies.

Contents

Introduction


The Development of Clinical Trials
General Statistical Issues
The Cochrane Collaboration
Cancer


Breast Cancer
Childhood Cancer
Gastrointestinal Cancers
Melanoma
Respiratory Cancers
Adrenal Cortical Carcinoma
Thyroid Cancer
Urologic Cancers
Haematologic Cancers: Challenges in Developing New Therapeutic Approaches
Cardiology


Acute Stroke
Cardiovascular Disease
Dentistry and Oral Health Care


Dentistry and Oral Health Care
Dermatology


Dermatology
Infectious Diseases


HIV Infection
Infectious Diseases
Ophthalmology


Ophthalmology
Psychiatry


Anxiety Disorders
Cognitive Behaviour Therapy
Psychotherapy for Depression
Reproductive Health


Contraception
Gynaecology and Infertility
Early Pregnancy Termination
Maternal and Perinatal Health
Respiratory


Respiratory Medicine
Surgery and Anaesthesia


Anaesthesia and Pain
General Surgery
Plastic Surgery – Reconstructive Surgery
Plastic Surgery – Aesthetic Surgery
Transplantation


Renal Transplantation
Other Processes


Wound Healing
Palliative Care
Complementary Medicine
Cluster Randomized Trials in Health Care Research
Nursing
Special Populations


Clinical Trials in Paediatrics
Clinical Trials Involving Older People
Clinical Trials in Rare Diseases
Index



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