Scent and Chemistry The Molecular World of Odors by Günther Ohloff

Scent and Chemistry
The Molecular World of Odors
by Günther Ohloff

Scent and Chemistry: The Molecular World of Odors presents a vivid and up-to-date picture of the chemistry of odorants and the research in odor perception.

Coverage includes:

• the molecular basis of olfaction
• olfactory characterization of perfumery materials
• structure-odor relationships
• chemical synthesis of odorants
• chemistry of essential oils and odorants from the animal kingdom
• notes in perfumery for each essential oil

Contents

1. Historical Aspects

• Scents of Time
• Chemical Discoveries and Modern Perfumery

2. The Chemical Senses

• Anatomy, Physiology, and Biochemistry of Olfactory Receptors
• Historical Aspects
• Description and Classification of Odor Impressions
• Historical AspectsQuantitative Odor Perception

3. Structure-Odor Relationships

• Physicochemical Properties of Odorants and the Concept of Osmophoric Groups
• Structure-Odor Correlations
• Molecular Shape and Odor – The Early Theories
• The Concept of Profile and Bulky Groups
• Unsaturated Compounds
• Diastereoisomers
• Steroid-Type Odorants
• Odor Rules
• Bifunctional Units: Mugent and Caramel Odorants
• QSAR: Homology vs. Olfactophore Models
• Enantioselectivity of the Odor Sensation

4. Odorants from Natural Sources

• Important Terpene Building Blocks
• Odorants from α- and β-Pinene
• Synthetic Odorants from Cyclic Monoterpenes
• Acyclic Odorants of the Monoterpene Series
• Odorants from 3,7-Dimethylocta-1,6-diene
• Odorants by Functionalization of Myrcene
• Odorants from (-)-Caryophyllene and (+)-Longifolene
• Odorants from α=Cedrene and Thujopsene

5. Odorants from Petrochemical Sources

• Isoprene as Starting Material for the Synthesis of Odorants
• Isobutene and 3-Methylbut-1-en-2-ol as Starting Materials
• Terpenoids from Isobutene
• (-)-Menthol

6. Ionones, Damascones, and Iso E Super

• Violet and Orris Odorants
• Rose Ketones
• Isocyclemones: Ionone-Type materials in Perfumery

7. Essential Oils

• Citrus Oils
• Petigrain Oil
• Neroli Oil/Orange Blossoms
• Lavender Oil
• Clary Sage Oil
• Patchouli Oil
• Jasmine Absolute
• Rose Oil
• Geranium Oil
• Violet Oil
• Orris
• Osmanthus Oil
• Vetiver Oil
• Cedarwood Oil
• Sandalwood Oil
• Galbanum
• Labdanum
• Oakmoss
• Incense and Myrrh
• Black and Pink Pepper

8. Odorants of Animal Origin

• Musk and Civet
• Industrial Synthesis of Macrocyclic Odorants
• Non-Natural Musks
• Ambergris
• Castoreum

Index