The second edition of this classic text has been completely revised, updated, and extended to include chapters on biomimetic amination reactions, Wacker oxidation, and useful domino reactions.

The first-class author team with long-standing experience in practical courses on organic chemistry covers a multitude of preparative procedures of reaction types and compound classes indispensable in modern organic synthesis. Throughout, the experiments are accompanied by the theoretical and mechanistic fundamentals, while the clearly structured sub-chapters provide concise background information, retrosynthetic analysis, information on isolation and purification, analytical data as well as current literature citations. Finally, in each case the synthesis is labeled with one of three levels of difficulty.

An indispensable manual for students and lecturers in chemistry, organic chemists, as well as lab technicians and chemists in the pharmaceutical and agrochemical industries.

1 C-C BOND FORMATION
1.1 Nucleophilic Addition to Aldehydes, Ketones, Carboxylic Acid Derivatives (Esters, Anhydrides) and alpha,beta-Unsaturated Carbonyl Compounds;
Carbonyl Olefination
1.2 Alkylation of Aldehydes/Ketones, Carboxylic Acids, and beta-Dicarbonyl Compounds
1.3 Reactions of the Aldol and Mannich Type
1.4 Electrophilic and Nucleophilic Acylation
1.5 Reactions of Alkenes via Carbenium Ions
1.6 Transition-Metal-Catalyzed Reactions
1.7 Pericyclic Reactions
1.8 Radical Reactions

2 OXIDATION AND REDUCTION
2.1 Epoxidation of C=C Bonds
2.2 Dihydroxylation of C=C Bonds
2.3 Oxidation of Alcohols to Carbonyl Compounds
2.4 Enantioselective Reduction of Ketones
2.5 Biomimetic Reductive Amination *NEW*
2.6 Enantioselective Wacker Oxidation for the Synthesis Of Chromans *NEW*

3 HETEROCYCLIC COMPOUNDS
3.1 Three- and Four-Membered Heterocycles
3.2 Five-Membered Heterocycles
3.3 Six-Membered Heterocycles
3.4 Condensed Heterocycles
3.5 Other Heterocyclic Systems;
Heterocyclic Dyes

4 SELECTED NATURAL PRODUCTS
4.1 Isoprenoids
4.2 Carbohydrates
4.3 Amino Acids and Peptides
4.4 Nucleotides and Oligonucleotides

5 DOMINO REACTIONS *NEW*
5.1 Domino Reactions in Synthetic Methodology
5.2 Domino Reactions in The Synthesis of Alkaloids
5.3 Domino Reactions in The Synthesis of Isoprenoids
5.4 Domino Reactions for The Synthesis of Chromans And Dioxins
5.5 Domino Reactions in The Synthesis of Chiroptical Switches

6 INDEX OF REACTIONS
7 INDEX OF PRODUCTS
8 SUBJECT INDEX