Classics in Stereoselective Synthesis By Erick M. Carreira, Lisbet Kvaerno
Classics in Stereoselective Synthesis
Conformational Control in Medium-Sized Rings.
Asymmetric Synthesis with Medium-Sized Rings.
Case Studies in Natural Products Total Synthesis.
Macrocyclic Stereocontrol in Cyclic Peptides.
Appendix: Macrocycle Formation.
CARBONYL ADITION REACTIONS.
Non-Chelated 1,2-Asymmetric Induction and the Operation of Steric and Electronic Effects.
1,2-Asymmetric Induction Predicated on Chelation Control.
1,3-Asymmetric Induction from CBeta Stereogenic Centers.
Asymmetric Induction by Remote Stereocenters (Beyond 1,3-Induction).
Catalytic Enantioselective Carbonyl Additions of Arganozinc Species.
Enantioselective Ketone Reduction.
Enzymatic Reduction of Ketones.
Enantioselective Formation of Cyanohydrins.
Enantioselective Alkyne Additions.
Asymmetric Carbonyl-Ene Reactions.
ALPHA-FUNCTIONALIZATIONS OF ENOLATES.
Diastereoselective Alpha-Alkylations of Chiral Enolates.
Asymmetric Enolate Alkylations Using Chiral Auxiliaries.
Enantioselective Enolate Alkylations.
Alpha-Hydroxylations of Enolates.
Alpha-Halogenations of Enolates.
Chiral Enolates Through the Use of Chiral Auxiliaries or Chiral Controller Groups.
Substrate Control with Chiral Carbonyl Compounds.
Catalytic Enantioselective Aldol Reactions.
ALLYLATIONS OF C=O BONDS.
Reactivity of Allylmetal Reagents.
Enantioselective Additions of Optically Active Allylic Boron Reagents.
Diastereoselecive Allylations with Chiral Boron Reagents.
Mechanistic Aspects - Lewis Acid-Promoted Addition of Allylsilanes and Allylstannanes to Aldehydes.
Chelation Control in the Allylation of Alpha- and Beta-Alkoxy Aldehydes.
Diastereoselective Allylations with Chiral Silanes and Stannanes.
Catalytic Asymmetric Allylations.
Diastereoselective Reactions of Chiral Acetals.
Spiroketals in Natural Product Synthesis.
Hydroborations with Acyclic Stereocontrol.
Asymmetric Hydroborations with Chiral Boranes.
Catalytic Asymmetric Hydroboration, Hydrosilylation, and Hydroalumination.
REDUCTIONS OF OLEFINS.
Diastereoselective Olefin Reductions by Catalytic Hydrogenation.
Alternative Methods for Diastereoselective Olefin Reductions.
Catalytic Asymmetric Olefin Hydrogenations.
OXIDATIONS OF OLEFINS.
Asymmetric Ring-Opening of Epoxides.
Synthesis of Aziridines.
Iodolactonizations and Other Olefin Cyclizations Induced by Electrophiles.
Diastereoselective Dihydroxylations of Olefins.
Enantioselective Dihydroxylations of Olefins.
Enantioselective Aminohydroxylation of Olefins.
Enantioselective Hydrogenations of Alpha, Beta-Didehydroamino Acids.
Enolate Alkylations in the Presence of Chiral Auxiliaries.
Alkylation of Glycine Anion Equivalents in the Presence of Chiral Phase-Transfer Catalysts.
Enzymatic Syntheses of Alpha-Amino Acids.
Catalytic Asymmetric Strecker Reactions.
ADDITIONS TO C=N BONDS.
Substrate-Controlled Diastereoselective Additions to C=N Bonds.
Additions to Imine Derivatives Bearing N-Bound Auxiliaries.
Formation of Beta-Lactams Through Staudinger Reactions.
Intramolecular Diastereoselective Iminium Ion Cyclizations.
Catalytic Asymmetric Reductions of Imines and Imine Derivatives.
Catalytic Enantioselective Mannich and Mannich-Type Reactions.
Enantioselective Additions of Carbon Nucleophiles to C=N Bonds.
Diastereoselective Conjugate Additions.
Diastereoselective Conjugate Additions with Use of Chiral Auxiliaries.
Enantioselective Conjugate Additions of Enolates and other Stabilized Carbon Nucleophiles.
Enantioselective Conjugate Additions of Organometallic Species.
Enantioselective Conjugate Additions of Radicals.
Enantioselective Conjugate Additions of Heteroatom Nucleophiles.
Catalytic Enantioselective Stetter Reactions.
Organolithium Reagents by Transmetalation of Organostannanes.
Carbanions by Reductive Methods.
Chiral Carbanions by Deprotonation.
Sulfoxide- and Phosphorus-Stabilized Carbanions.
Metal-Mediated Enantioselective Olefin Functionalizations.
Diastereoselective Palladium-Catalyzed Allylation Reactions.
Enantioselective Palladium-Catalyzed Allylation Reactions.
Iridium-Catalyzed Enantioselective Allylation Reactions.
Copper-Catalyzed SN2' Allylation Reactions.
Enantioselective Allylation Reactions Catalyzed by Other Transition Metals.
Asymmetric Ring-Opening Reactions of Unsaturated Heterocycles.
CYCLOPROPANATIONS AND C-H INSERTION REACTIONS.
Diastereoselective Cyclopropanations with Carbenoids Generated from Diazoalkanes.
Enantioselective Dyclopropanations with Carbenoids Generated from Diazoalkanes.
Diastereoselective Simmons-Smith Cyclopropanations.
Enantioselective Simmons-Smith Cyclopropanations.
Alternative Classes Cyclopropanations.
Diastereoselective C-H Bonds.
Claisen and Claisen-Type [3,3]-Sigmatropic Rearrangements.
Cope and Cope-Type [3,3]-Sigmatropic Rearrangements.
DIELS-ALDER AND HETERO-DIELS-ALDER REACTIONS.
Diastereoselective Intermolecular Diels-Alder Reactions.
Diastereoselective Intramolecular Diels-Alder Reactions.
Diastereoselective Diels-Alder Reactions Using Chiral Auxiliaries.
Catalytic Enantioselective Diels-Alder Reactions.
Diastereoselective Hetero-Diels-Alder Reactions.
Enantioselective Hetero-Diels-Alder Reactions.
[3+2]- AND [2+2]-CYCLOADDITION REACTIONS.
Substrate-Controlled Diastereoselective [1,3]-Dipolar Cycloadditions.
Diastereoselective [1,3]-Dipolar Cycloadditions Using Chiral Auxiliaries.
Catalytic Enantioselective [1,3]-Dipolar Cycloadditions.
[3+2]-Cycloadditions with Trimethylenemethane Equivalents.