Chromatography Concepts and Contrasts Second edition

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Concepts and Contrasts
Second edition
by James M. Miller

The first edition of Chromatography: Concepts and Contrasts, published in 1988, was one of the first books to discuss all the different types of chromatography under one cover.

This new second edition continues with these principles but has been updated to include new chapters on sampling and sample preparation, capillary electrophoresis and capillary electrochromatography (CEC), chromatography with mass spec detection, and industrial and governmental practices in regulated industries.


  • Covers extraction, solid phase extraction (SPE), and solid phase microextraction (SPME), and introduces mass spectrometry
  • Updated with the latest techniques in chromatography
  • Discusses both liquid chromatography (LC)and gas chromatography(GC)



  1. Impact of Industrial and Government Regulatory Practices on Analytic Chromatography
  2. Introduction to Chromatography
  3. Band Broadening and Kinetics
  4. Physical Forces and Interactions
  5. Optimization and the Achievement of Separation
  6. Comparisons Between Chromatographic Modes
  7. Gas Chromatography
  8. Liquid Chromatography in Columns
  9. Quantitation: Detectors and Methods
  10. Chromatography with Mass Spectral Detection (GC/MS and LC/MS)
  11. Liquid Chromatography on Plane Surfaces
  12. Qualitative Analysis
  13. Capillary Electrophoresis and Capillary Electrochromatography
  14. Sample Preparation
  15. Special Applications
  16. Selection of a Method

Appendix: ICH Glossary

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