Biodrug Delivery Systems: Fundamentals, Applications and Clinical Development BY Mariko Morishita, Kinam Park

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Biodrug Delivery Systems: Fundamentals, Applications and Clinical Development

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Summary

 

Biodrug Delivery Systems: Fundamentals, Applications and Clinical Development presents the work of an international group of leading experts in drug development and biopharmaceutical science who discuss the latest advances in biodrug delivery systems and associated techniques. The book discusses components of successful formulation, delivery, and production of biodrugs, which include sophisticated plants and complex processes, a well-trained and knowledgeable staff, and proper quality control. In addition, the authors examine:

 

    • ADME (Absorption, Metabolism, Distribution, and Elimination of biodrugs)
    • Directing and influencing the successful development of currently marketed best-selling biodrugs
    • Routes of administration
    • Mechanisms of biodrug absorption
    • Alternative possibilities for drug delivery routes
    • Formulationson the market from the perspective of industry personnel involved in biodrug development

     

    Table of Contents

     

    Overview of Biodrug Delivery System
    Issues in Biodrug Delivery System
    Pharmacokinetic Consideration of Biodrugs
    Specific Route of Delivery
    Parenteral Delivery
    Brain Delivery
    Ocular Delivery
    Nasal Delivery
    Buccal Delivery
    Pulmonary Delivery
    Transdermal Delivery
    Colon Delivery
    Oral Delivery
    Cellular Delivery
    Delivery Systems
    Targeting: PK Consideration
    Monoclonal Antibody
    Receptor-Mediated Endocytosis
    Bioadhesive Delivery System
    Modified Release Delivery System
    Nanoparticulate Delivery System
    Lipid-Based Delivery System
    Implantable Delivery System
    Modifying the Physiochemical Nature of Biodrugs
    Regulatory Perspective of Biodrug Development
    Development of Biodrug Products
    Leuplin
    ANP (Atrial Natriuretic Peptide)
    Amylin And GLP-1 Agonists
    GHRP-2 (Growth Hormone Releasing Peptide)
    Endothelin Receptor Antagonist
    Angiotensin II Receptor Antagonist
    Insulin (Inhalation)
    Calcitonin
    Sandstatin LAR
    Interferon
    Vaccine
    Perspective of Biodrug Products

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