Science of Synthesis: Photocatalysis in Organic Synthesis

Description

The use of light in organic synthesis, more specifically the use of visible light in photoredox catalysis, has developed rapidly over the last 15 years and it is now time to define its impact on the field.

Aimed at both newcomers to the field and experts alike, Photocatalysis in Organic Synthesis introduces the important basic concepts of photophysics and describes typical laboratory set-ups for photoredox catalysis, thus enabling instant and reliable application of these new synthetic tools. Key photocatalytic transformations are discussed in detail, including representative experimental procedures, followed by a collection of industrial case studies. Rather than aiming for a comprehensive coverage, solutions are presented for challenging transformations in synthesis that employ visible light and suitable dyes. To this end, the authors, a team of pioneers and leaders in the field, discuss both the practical and conceptual aspects of this rapidly growing area of synthetic chemistry. A primary objective is to present a collection of the most useful, practical, and reliable methods of photocatalysis to a wider audience.

Table of Contents:

1 Introduction
2 Photocatalysis: The Principles
3 Practical Aspects of Photocatalysis
4 Photocatalytic Oxidative C-C Bond Formation
5 Decarboxylative Coupling Reactions
6 Proton-Coupled Electron Transfer
7 Organocatalysis with Amines in Photocatalysis
8 Copper-Based Photocatalysts for Visible-Light-Mediated Organic Transformations
9 Gold in Photocatalysis
10 Palladium in Photocatalysis
11 Nickel in Photocatalysis
12 Acridinium Dyes and Quinones in Photocatalysis
13 Flavins in Photocatalysis
14 Organic Dyes in Photocatalytic Reductive C-H Arylations
15 Silicates in Photocatalysis
16 Photocatalytic Cycloadditions
17 Photocatalytic Carbon-Heteroatom Bond Formation
18 Photocatalytic Introduction of Fluorinated Groups
19 Heterogeneous Photocatalysis in Organic Synthesis
20 Photocatalysis in the Pharmaceutical Industry